BIODOT LTD
- THE KINGLEY CENTRE DOWNS ROAD
WEST STOKE
PO18 9HJ CHICHESTER, WEST SUSSEX
Phone: 44.1243.572044
Fax: 44.1243.575752
E-mail: Send messagewww.biodot.com
Short profile:
BioDot uses its core competencies in low volume non-contact & contact dispensing, cutting/slitting, lamination & strip assembly, to develop a range of equipment for research, development & commercialization of diagnostic tests.
AirJet Quanti:
This configuration uses an aerosol type of dispense nozzle that using pressurized air to atomize the fluid passing through the nozzle. This creates a quantitative spray format where a dot or line can be quantitatively generation on a continuous basis. AirJet technology is non-contact, quantitative aerosol dispensing. BioDot's proprietary technology couples any one of the three AirJets with a high resolution syringe pump to meter exact amounts of reagents. This process produces a precise and easy to use method for dispensing microliter quantities of fluids. Unique design features ensure repeatability and allow for disassembly and cleaning without affecting calibration.
Detailed description:
BioDot is the leading supplier of system tools for the research, development and commercialization of diagnostic tests. Our mission is to enable, inspire and educate scientists to commercialize their R&D ideas through to manufactured product. Using its core competencies in low volume non-contact dispensing, cutting/slitting, lamination, and strip assembly, BioDot has developed a range of equipment for the research and development, and manufacture of rapid tests.
Lateral Flow Immunoassays are used by point-of-care markets for immunological testing. Examples of utilization of immunoassays include cholesterol, cardiac arrest, diabetes testing. Recently, and due to some constraining patent issues, many manufacturers of lateral flow assays have invested into R&D to develop multiplexing assays on complex platforms for very specific applications, and to improve the design of current lateral flow substrate to increase reproducibility in the final product.
The lateral flow immunoassay format was developed in the seventies and within 10 years became a standard platform for a variety of Point of Care (POC) tests. The benefits of this format were:
Ease of use.
Requires relatively small amount of sample.
Adequate level of sensitivity.
Ease of manufacture in large scale.
Stability of the final product at room temperature (shelf life).
Ease of implementation with a reader technology.
Ease of approval by regulatory instances (format well know by the market).
Relatively inexpensive to manufacture.
For many tests, this format was very attractive. However, recent market needs have evolved into higher demands, requiring LFIA tests to produce more than the traditional “yes/no” result. The progression of lateral flow tests to true quantitative formats is an active area of current research and development.
Keywords:
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